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Academic Article
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Id4 deficiency attenuates prostate development and promotes PIN-like lesions by regulating androgen receptor activity and expression of NKX3.1 and PTEN.
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Academic Article
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Increased expression of bHLH transcription factor E2A (TCF3) in prostate cancer promotes proliferation and confers resistance to doxorubicin induced apoptosis.
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Academic Article
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Inhibitor of differentiation 4 (ID4) acts as an inhibitor of ID-1, -2 and -3 and promotes basic helix loop helix (bHLH) E47 DNA binding and transcriptional activity.
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Academic Article
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Id4 promotes senescence and sensitivity to doxorubicin-induced apoptosis in DU145 prostate cancer cells.
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Academic Article
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Id4 dependent acetylation restores mutant-p53 transcriptional activity.
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Academic Article
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Basic helix loop helix (bHLH) transcription factor 3 (TCF3, E2A) is regulated by androgens in prostate cancer cells.
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Academic Article
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The helix-loop-helix inhibitor of differentiation (ID) proteins induce post-mitotic terminally differentiated Sertoli cells to re-enter the cell cycle and proliferate.
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Academic Article
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Negative acting HLH proteins Id 1, Id 2, Id 3, and Id 4 are expressed in prostate epithelial cells.
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Academic Article
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ID1-, ID2-, and ID3-regulated gene expression in E2A positive or negative prostate cancer cells.
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Concept
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Transcription Factors
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Concept
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E2F1 Transcription Factor
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Concept
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p300-CBP Transcription Factors
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Concept
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Basic Helix-Loop-Helix Transcription Factors
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Concept
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TCF Transcription Factors
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Concept
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Forkhead Transcription Factors
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Academic Article
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Role of basic-helix-loop-helix transcription factors in Sertoli cell differentiation: identification of an E-box response element in the transferrin promoter.
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Academic Article
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Role of specific response elements of the c-fos promoter and involvement of intermediate transcription factor(s) in the induction of Sertoli cell differentiation (transferrin promoter activation) by the testicular paracrine factor PModS.
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Academic Article
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Expression of the basic helix-loop-helix protein REBalpha in rat testicular Sertoli cells.
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Academic Article
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Basic helix-loop-helix proteins can act at the E-box within the serum response element of the c-fos promoter to influence hormone-induced promoter activation in Sertoli cells.
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Academic Article
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Role of winged helix transcription factor (WIN) in the regulation of Sertoli cell differentiated functions: WIN acts as an early event gene for follicle-stimulating hormone.
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Academic Article
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Suppression of c-Fos gene transcription with malignant transformation of human bronchial epithelial cells.
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Academic Article
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Hormonal regulation and differential actions of the helix-loop-helix transcriptional inhibitors of differentiation (Id1, Id2, Id3, and Id4) in Sertoli cells.
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Academic Article
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A Small-Molecule Pan-Id Antagonist Inhibits Pathologic Ocular Neovascularization.
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